Anti-ICOSL Antibody (Clone# ICOSL/3111)

Anti-ICOSL Antibody (Clone# ICOSL/3111)is available at Gentaur for Next week Delivery.

Description: ICOSL (also known as B7-H2, CD275) is a cell surface antigen that belongs to the family of B7 proteins. It is constitutively expressed by antigen-presenting cells (APCs) such as B cells, dendritic cells, and activated monocytes. It is also the ligand for ICOS, a cell-surface receptor that is expressed by activated T cells. Binding of ICOSL to ICOS leads to activation and proliferation of T cells, as well as the survival of memory T cells. ICOSL plays an important role in diseases such as rheumatoid arthritis, systemic lupus erythematosus, and uveitis, where it triggers the release of cytokines such as IL-10, IL-4, and IFN-γ. ICOSL expression has been observed in several cancers; however, its role is not yet determined.

Immunogen Sequence:Recombinant fragment of human ICOSL protein (aa 23-149)

Target Alternative Name:B7h, B7H2, GL50, B7-H2, B7RP1, CD275, ICOSL, LICOS, B7RP-1, ICOS-L, ICOSLG

Species Reactivities:Human

Tag Line:Mouse monoclonal antibody to detect the expression of ICOSL in human samples

Formulation:In 10 mM PBS

Purification: Protein A/G purified

Application:Immunohistochemistry (IHC) Immunofluorescence (IF) Flow Cytometry

Positive Control:/

Application And Usages:FC (1-2 µg/million cells), IF (1-2 µg/ml), IHC (1-2 µg/ml)

Handling:The antibody solution should be gently mixed before use.