Anti-HER2 (Trastuzumab), Humanized Antibody

Anti-HER2 (Trastuzumab), Humanized Antibodyis available at Gentaur for Next week Delivery.

Description: Trastuzumab is a recombinant humanized monoclonal immunoglobulin G1 kappa antibody that binds with high affinity and specificity to the extracellular domain of the HER2 receptor. A growth factor receptor gene, human epidermal growth factor receptor (HER2), is amplified in 25 to 30 % of breast cancers and in these cases the encoded protein is present in abnormally high levels in the malignant cells. Trastuzumab is used to treat adjuvant and metastatic breast cancer as well as metastatic gastric cancer.

Immunogen Sequence:Recombinant human epidermal growth factor receptor 2 (HER2)

Target Alternative Name:Neu, Ngl, Erbb2, Tkr1, Cd340, Her-2, Mln 19, HER-2/neu, RHUMAB HER2, 4D5V8, ABP 980, ABP-980, DMB-3111, EG-12014, EG12014, R-597, SB-3, SYD-977, SYD977

Species Reactivities:Human

Tag Line:Monoclonal human IgG1 antibody against human HER2

Formulation:100 ug (2 mg/ml) of antibody in Phosphate buffered saline, pH 7.4.

Purification: human IgG1 was expressed in a human cell line. IgG was purified from CHO cell culture supernatant by protein A chromatography.

Application:Neutralization, ELISA

Positive Control:/

Application And Usages:Neutralization : 1-20 μg/ml; ELISA: 2μg/ml

Handling:The antibody solution should be gently mixed before use