Anti-HER2 (c-erbB-2), Rabbit Monoclonal Antibody

Anti-HER2 (c-erbB-2), Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor receptor. HER2 is an oncogene and overexpression of unaltered HER2 coding sequences in NIH 3T3 cells results in cellular transformation and tumorigenesis. HER2 is amplified in about 30% of primary human breast malignancies and overexpression of HER2 is associated with the most aggressive tumors that show uncontrolled proliferation, resistance to apoptosis and increased motility.

Immunogen Sequence:A peptide corresponding to the C-terminus of Human c-erbB-2/HER-2

Target Alternative Name:Metastatic lymph node gene 19 protein, MLN 19, HER2, MLN19, NEU, NGL, ERBB2

Species Reactivities:Human

Tag Line:Rabbit monoclonal antibody to detect HER2 in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified using protein A

Application:IHC, WB

Positive Control:WB: MCF-7, PC3, Jurkat, A375; IHC: human breast cancer tissue

Application And Usages:IHC: 1:100 dilution; WB: 1:1000 dilution

Handling:The antibody solution should be gently mixed before use.