Anti-H2BK12me1 Antibody

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SKU:
A2048-100
€325
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Description

Anti-H2BK12me1 Antibodyis available at Gentaur for Next week Delivery.

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack poly A tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Immunogen Sequence:A methylated peptide sequence targeting residues around Lysine 12 of human Histone H2B

Target Alternative Name:Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l), HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI, H2BFL; H2BFH; H2BFG; H2BFA; H2BFK

Species Reactivities:Human

Tag Line:Rabbit polyclonal antibody to detect monomethylation of Histone H2B at Lysine 12 in human samples

Formulation:In 0.01 M PBS, 50% glycerol, 0.03% proclin 300, pH 7.4

Purification: Antigen Affinity purified

Application:ChiP, Immunocytochemistry (ICC), Western Blotting

Positive Control:/

Application And Usages:WB 1:100-1:1000, ICC 1:20-1:200

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µl
Antibody Target:
HIST1H2BC
Category:
Antibody
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
IgG
Accession Number:
P62807
Gene Id:
8347
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
WB data verified using A549, K562, HepG2 and Jurkat whole cell lysate
Immunocytochemistry Verified:
False
Immunofluorescence Verified:
False
Immunoprecipitation Verified:
False
FACS Verified:
False
ELISA Verified:
False
ChIP Verified:
True
Dot Blot Verified:
False
Flow Cytometry Verified:
False
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