Anti-H mgB1Monoclonal Antibody (Clone: ABM2E44)

Anti-H mgB1Monoclonal Antibody (Clone: ABM2E44)is available at Gentaur for Next week Delivery.

Description: H mgB1 (High-mobility group protein B1) is a 25 kDa non-histone chromatin protein, secreted by immune cells through leaderless secretory pathway. H mgB1 supports transcription and also interacts with nucleosomes to loosen packed DNA and remodel the chromatin. The presence of H mgB1 in the nucleus depends on posttranslational modifications. When the protein is not acetylated, it stays in the nucleus, but hyperacetylation on lysine residues causes it to translocate into the cytosol. H mgB1 has the ability to bend DNA in order to facilitate binding of other proteins to the DNA. H mgB1 has one important role in V(D)J recombination where act as a cofactor of the RAG complex. H mgB1 stimulates a plethora of cellular responses like inflammation, attracting inflammatory cells, recruiting stem cells and promoting their proliferation. H mgB1 is highly expressed in human kidney, tonsils, adipose tissue, adrenal cortex and amniotic fluid.

Immunogen Sequence:A partial length recombinant H mgB1 protein (amino acids 1- 200) was used as the immunogen

Target Alternative Name:H mgB1,H mg1

Species Reactivities:Human

Tag Line:Monoclonal antibody for the detection of H mgB1 in cells

Formulation:0.5 mg/ml in Supplied in PBS containing 0.05% BSA and 0.05% Sodium azide.

Purification: Protein G Chromatography

Application:WB

Positive Control:/

Application And Usages:WB: 2-4 mg/ml

Handling:The antibody solution should be gently mixed before use