Anti-H mg CoA Reductase Antibody

Anti-H mg CoA Reductase Antibodyis available at Gentaur for Next week Delivery.

Description: H mg-CoA reductase (3-hydroxy-3-methyl-glutaryl-CoA reductase or H mgR) (EC 1.1.1.34) is a transmembrane protein involved in the mevalonate pathway, the metabolic pathway that produces cholesterol from acetyl-CoA. In an NADPH-dependent reaction, H mg-CoA reductase reduces H mg-CoA to generate mevalonate and CoA. Since H mg-CoA reductase catalyzes the rate limiting step in cholesterol synthesis, it is a primary target of a group of cholesterol-lowering drugs known as statins. Inhibition of H mg-CoA reductase induces expression of LDL receptors in the liver, which lowers plasma concentration of cholesterol.

Immunogen Sequence:GST Tagged recombinant human H mg-CoA Reductase Catalytic Domain (aa 426–888)

Target Alternative Name:3-Hydroxy-3-methylglutaryl-CoA reductase, H mgR, H mgCR

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect H mg CoA Reductase

Formulation:In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.

Purification: Affinity purified

Application:WB

Positive Control:WB: Rat kidney lysate, HeLa, HepGe cell lysate, H mg CoA human recombinant

Application And Usages:WB: 1-4 µg

Handling:The antibody solution should be gently mixed before use