Anti-Connexin 32 Antibody (GJB1/1753)

Anti-Connexin 32 Antibody (GJB1/1753)is available at Gentaur for Next week Delivery.

Description: This Ab recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane -helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.

Immunogen Sequence:Recombinant human GJB1 protein

Target Alternative Name:Charcot Marie Tooth neuropathy X linked; CMTX; CMTX1; Connexin-32; Cx32; GAP junction 28kDa liver protein; Gap junction beta-1 protein; Gap junction protein beta 1 32 kD; GJB1

Species Reactivities:Human, Mouse and Rat

Tag Line:Monoclonal Antibody to detect Connexin 32 in human samples

Formulation:Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein G purified

Application:FC, IF, WB, IHC

Positive Control:IHC: human Liver, human Tonsil

Application And Usages:FC: 0.5-1 µg/1X106 cells, IF: 1-2 µg/ml, WB: 0.5-1 µg/ml, IHC: 1-2 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use