Anti-Clathrin Antibody (CLC/1421)

Anti-Clathrin Antibody (CLC/1421) is available at Gentaur for Next week Delivery.

Description: This antibody recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Immunogen Sequence:Purified recombinant N-terminal fragment of human Clathrin Light Chain

Target Alternative Name:Clathrin light chain A; Clathrin light chain B; Clathrin light chain LCA; Clathrin light chain LCB; Clathrin light polypeptide A; Clathrin light polypeptide B; Clathrin, light polypeptide (Lca); Clathrin, light polypeptide (Lcb); CLTA; CLTB

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect Clathrin in human samples

Formulation:Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purified

Application:FC, IF, IHC

Positive Control:IHC: Human Pancreas

Application And Usages:FC: 0.5-1 µg/1X106 cells, IF: 1-2 µg/ml, IHC: 0.5-1 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use