Anti-CFTR Antibody (SPM176)

Anti-CFTR Antibody (SPM176) is available at Gentaur for Next week Delivery.

Description: This mAb recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3', 5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Immunogen Sequence:Recombinant human full-length CFTR

Target Alternative Name:ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7); cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR, ABCC7

Species Reactivities:Human and Mouse

Tag Line:Monoclonal Antibody to detect CFTR in human samples

Formulation:Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purified

Application:WB, IF, IHC

Positive Control:IHC: Human Pancreas

Application And Usages:WB: 0.5-1 µg/ml, IF: 0.5-1 µg/ml, IHC: 0.5-1.0 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use