Anti-CD99 / MIC2 Antibody (MIC2/877)

Anti-CD99 / MIC2 Antibody (MIC2/877)is available at Gentaur for Next week Delivery.

Description: Recognizes a sialoglycoprotein of 27-32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis. CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors.

Immunogen Sequence:Recombinant full-length human MIC2 protein

Target Alternative Name:12E7; E2 antigen; MIC 2X; MIC 2Y; MIC2; Protein MIC2; Surface antigen MIC2; T-cell surface glycoprotein E2

Species Reactivities:Human, does not react with Rat.

Tag Line:Monoclonal Antibody to detect CD8A in human samples

Formulation:Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Ewing's Sarcoma, human Ovarian Carcinoma, human Testicular Carcinoma

Application And Usages:FC: 0.5-1 µg/1X106 cells in 0.1ml, IF: 0.5-1 µg/ml, IHC: 1-2 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use