Description
Anti-CD8A Antibody (C8/468)is available at Gentaur for Next week Delivery.
Description: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α/β) or as a homodimer (CD8 α/α). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Immunogen Sequence:Human CD8 recombinant protein
Target Alternative Name:CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain
Species Reactivities:Human
Tag Line:Monoclonal Antibody to detect CD8A in human samples
Formulation:Supplied in 10 mM PBS with 0.05% BSA & 0.05% azide
Purification: Protein A/G purification
Application:FC, IF, IHC
Positive Control:IHC: human Tonsil
Application And Usages:FC: 0.5-1 µg/1X106cells in 0.1ml, IF: 0.5-1 µg/ml, IHC: 0.5-1 µg/ml for 30 minutes at RT
Handling:The antibody solution should be gently mixed before use
Additional Information
Size: |
100 µg |
Antibody Target: |
CD8A |
Category: |
Immunology |
Host: |
Mouse |
Antibody Type: |
Monoclonal |
Isotype: |
Mouse / IgG1, kappa |
Accession Number: |
P01732 |
Gene Id: |
925 |
Appearance: |
Colorless liquid |
Form: |
Liquid |
Storage Condition: |
-20 °C |
Shipping Condition: |
gel pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
USA |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans |
Western Blot Verified: |
Not Verified |
Immunocytochemistry Verified: |
Verified |
Immunofluorescence Verified: |
Not Verified |
Immunoprecipitation Verified: |
Not Verified |
FACS Verified: |
Not Verified |
ELISA Verified: |
Not Verified |
ChIP Verified: |
Not Verified |
Dot Blot Verified: |
Not Verified |
Flow Cytometry Verified: |
Not Verified |