Anti-CD74 Antibody (B-Cell Marker) (Clone LN-2)

Anti-CD74 Antibody (B-Cell Marker) (Clone LN-2)is available at Gentaur for Next week Delivery.

Description: It recognizes a protein of ~35 kDa, identified as CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating a typical fibroxanthoma (-) from malignant fibrous histiocytoma (+).

Immunogen Sequence:SU-DHL-4 lymphoma cells

Target Alternative Name:DHLAG, Gamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, HLADR-gamma (HLADG), Ia antigen-associated invariant chain, la-gamma, Major histocompatibility complex class II invariant chain, CLIP, MHC HLA-DR gamma chain, p33, CD74

Species Reactivities:Human, Baboon and Mouse. Does not react with rat

Tag Line:Monoclonal Antibody to detect CD74 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Tonsil

Application And Usages:FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 1-2 µg/ml, IHC: 1-2 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use