Anti-CD61/ Integrin beta-3 / Platelet Glycoprotein IIIa Antibody (CloneY2/51)

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SKU:
A1556-100
£289.03
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Description

Anti-CD61/ Integrin beta-3 / Platelet Glycoprotein IIIa Antibody (CloneY2/51)is available at Gentaur for Next week Delivery.

Description: Reacts with human integrin beta-3 (GPIIIa, vitronectin receptor beta chain). It associates with the V-chain (CD51) to form vitronectin receptor, or with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61). The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.

Immunogen Sequence:Phytohemagglutinin (PHA)-stimulated peripheral blood cells

Target Alternative Name:BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD61 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Spleen

Application And Usages:FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 0.5-1 µg/ml, IHC: 1-2 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use

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Additional Information

Size:
100 µg
Antibody Target:
CD61
Category:
Immunology
Host:
Mouse
Antibody Type:
Monoclonal
Isotype:
Mouse / IgG1, kappa
Accession Number:
P05106
Gene Id:
3690
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans
Western Blot Verified:
Not Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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