Anti-CD56 / NCAM1 Antibody (Clone SPM128)

Anti-CD56 / NCAM1 Antibody (Clone SPM128)is available at Gentaur for Next week Delivery.

Description: This mAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Immunogen Sequence:Membrane preparation of a small cell lung carcinoma

Target Alternative Name:NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule, CD56, NCAM-1, N-CAM-1

Species Reactivities:Human, Rat and Zebrafish

Tag Line:Monoclonal Antibody to detect CD56 / NCAM1 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Cerebellum, FACS: human Monocytes

Application And Usages:FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 0.5-1 µg/ml, IHC: 0.5-1.0 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use