Anti-CD45RB Antibody (Clone BRA-11(same as BRA-11G))

Anti-CD45RB Antibody (Clone BRA-11(same as BRA-11G))is available at Gentaur for Next week Delivery.

Description: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemia’s of B-cell origin.

Immunogen Sequence:Non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V)

Target Alternative Name:B220, CD45R, GP180, Leukocyte common antigen (LCA), Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C (PTPRC), Receptor-type tyrosine-protein phosphatase C, T200 glycoprotein

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD45RB in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Tonsil

Application And Usages:FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 0.5-1 µg/ml, IHC: 0.5-1.0 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use