Anti-CD4 (Campath-9H), Rabbit IgG, kappa Antibody

Anti-CD4 (Campath-9H), Rabbit IgG, kappa Antibodyis available at Gentaur for Next week Delivery.

Description: CD4 gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Anti-CD4 (Campath-9H) monoclonal antibody recognizes the 55 kDa human CD4 cell surface antigen. This chimeric rabbit antibody was made using the variable domain sequences of the original rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Immunogen Sequence:Rat T-cell line (NB2) transfected with the human CD4

Target Alternative Name:Cluster of differentiation 4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3

Species Reactivities:Human

Tag Line:Recombinant monoclonal antibody manufactured using Recombinant Platform with variable regions from the hybridoma YNB46.1.8 (Campath 9-H) to detect CD4 expression in humans

Formulation:Supplied in PBS, pH 7.5

Purification: SOURCE: CHO cells

Application:Immunohistochemistry (IHC), Western Blotting, IHC-Fr, Flow Cytometry

Positive Control:/

Application And Usages:WB, FC, IHC, IHC-Fr

Handling:The antibody solution should be gently mixed before use.