Anti-CD3e Antibody (C3e/1308)

Anti-CD3e Antibody (C3e/1308)is available at Gentaur for Next week Delivery.

Description: Recognizes the γ-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Immunogen Sequence:Recombinant human CD3e fragment (aa 23-119)

Target Alternative Name:CD 3E, CD3 epsilon, CD3 TCR complex, CD3E, CD3e antigen epsilon polypeptide (TiT3 complex), T cell antigen receptor complex epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE, TiT3 complex

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD3e in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Purified from rabbit anti-serum by Protein A

Application:FC, IF, WB, IHC

Positive Control:IHC: human Tonsil, WB: CD3e and Jurkat cell

Application And Usages:FC: 0.5-1 µg/1X106 cells, IF: 1-2 µg/ml, IHC: 1-2 µg/ml for 30 minutes at RT, WB: 1-2 µg/ml for 60 minutes at RT

Handling:The antibody solution should be gently mixed before use