Anti-CD30 / TNFRSF8 Antibody (CD30/412)

Anti-CD30 / TNFRSF8 Antibody (CD30/412)is available at Gentaur for Next week Delivery.

Description: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin’s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This mAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Immunogen Sequence:Human CD30 recombinant protein

Target Alternative Name:CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD30 / TNFRSF8 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Hodgkin's Lymphoma

Application And Usages:FC: 0.5-1 ug/1X106 cells in 0.1ml, IF: 1-2 ug/ml, IHC: 0.5-1 ug/ml

Handling:The antibody solution should be gently mixed before use