Anti-CD22 / BL-CAM Antibody (BLCAM/1795)

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SKU:
A1482-100
€395
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Description

Anti-CD22 / BL-CAM Antibody (BLCAM/1795)is available at Gentaur for Next week Delivery.

Description: Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Immunogen Sequence:Recombinant human BL-CAM/CD22 protein (aa52-178) (exact sequence is proprietary)

Target Alternative Name:B-lymphocyte cell adhesion molecule (BL-CAM); B-cell receptor CD22; CD22; Lectin 2; Lyb8; Sialic acid-binding Ig-like lectin 2 (Siglec-2); SIGLEC2; T-cell surface antigen Leu-14

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD22 / BL-CAM in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC, WB, ELISA

Positive Control:IHC: human Tonsil, WB: Analysis of Raji and Ramos Cell Lysates

Application And Usages:ELISA: Use Ab at 2-4ug/ml for coating, FC: 0.5-1ug/1X106 cells, IF: 0.5-1ug/ml, IHC: 1-2ug/ml for 30 minutes at RT, WB: 0.5-1ug/ml

Handling:The antibody solution should be gently mixed before use

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Additional Information

Size:
100 µg
Antibody Target:
CD22 / BL-CAM
Category:
Immunology
Lot Number:
N/A
Host:
Mouse
Antibody Type:
Monoclonal
Isotype:
Mouse / IgG1, kappa
Accession Number:
P20273
Gene Id:
933
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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