Anti-CD209 / DC-SIGN Antibody (C209/1781)

Anti-CD209 / DC-SIGN Antibody (C209/1781)is available at Gentaur for Next week Delivery.

Description: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

Immunogen Sequence:Recombinant human CD209 protein fragment

Target Alternative Name:CD209; CDSIGN; CIRE; CLEC4L; DC-SIGN; DC-SIGN1; DCSIGN; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD209/DC-SIGN in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Lung Carcinoma, human Colon Carcinoma, human Small Intestine

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 1-2 ug/ml, IHC: 0.5-1 ug/ml

Handling:The antibody solution should be gently mixed before use