Anti-CD1a / HTA1 Antibody (C1A/711)

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SKU:
A1478-100
£289.03
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Description

Anti-CD1a / HTA1 Antibody (C1A/711)is available at Gentaur for Next week Delivery.

Description: At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).

Immunogen Sequence:Recombinant human CD1a protein

Target Alternative Name:Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a antibody, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD1a / HTA1 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Skin

Application And Usages:FC: 0.5-1 ug/1X106 cells in 0.1ml, IF: 1-2 ug/ml, IHC: 0.5-1 ug/ml

Handling:The antibody solution should be gently mixed before use

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Additional Information

Size:
100 µg
Antibody Target:
CD1a / HTA1
Category:
Immunology
Lot Number:
N/A
Host:
Mouse
Antibody Type:
Monoclonal
Isotype:
Mouse / IgG1, kappa
Accession Number:
P06126
Gene Id:
909
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans
Western Blot Verified:
Not Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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