Anti-CD147 (Meplazumab), Humanized Antibody

Anti-CD147 (Meplazumab), Humanized Antibodyis available at Gentaur for Next week Delivery.

Description: This research-grade biosimilar is a humanized antibody that binds and inhibits CD147. CD147, also known as basigin, is a transmembrane glycoprotein of the immunoglobulin superfamily which acts as a surface receptor involved in tumor development, malaria, and bacterial and viral infections. CD147 has recently been implicated in SARS-CoV-2, wherein the viral spike proteins bind to the receptor. The original humanized monoclonal antibody is currently being investigated as a combinatorial therapy in patients with pneumonia associated with SARS-CoV-2.

Immunogen Sequence:FAUX

Target Alternative Name:Collagenase stimulatory factor Tumor cell-derived collagenase stimulator factor (TCSF) Extracellular matrix metalloprotease inducer (EMMPRIN) Basigin (BSG) HAb18G 5F7 SLC7A11

Species Reactivities:Human

Tag Line:Binds to and inhibits CD147, a receptor implicated in SARS-CoV-2 associated pneumonia

Formulation:In PBS, pH 7.5

Purification: FAUX

Application:FAUX

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.