Anti-Catenin, gamma Antibody (11 E4)

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SKU:
A1468-100
£289.03
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Description

Anti-Catenin, gamma Antibody (11 E4)is available at Gentaur for Next week Delivery.

Description: It recognizes a protein of 80-87kDa, identified as gamma-catenin. The catenins (α, β, γ and δ) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. α T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. α T-catenin binds to α E-catenin as well as to β-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for α-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.

Immunogen Sequence:Recombinant full length human plakoglobin, fused to maltose binding protein

Target Alternative Name:ARVD12; Catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; CTNNG; Desmoplakin III; Desmoplakin-3; DP3; DPIII; Junction Plakoglobin; PDGB; PKGB

Species Reactivities:Human, mouse

Tag Line:Monoclonal Antibody to detect Catenin, gamma in human and mouse samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, WB

Positive Control:WB: HT20, A549, 293 and A431 Cell Lysates

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 1-2 ug/ml, WB: 0.5-1ug/ml

Handling:The antibody solution should be gently mixed before use

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Additional Information

Size:
100 µg
Antibody Target:
Catenin gamma
Category:
Signal Transduction
Lot Number:
N/A
Host:
Mouse
Antibody Type:
Monoclonal
Isotype:
Mouse / IgG1, kappa
Accession Number:
P14923
Gene Id:
3728
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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