Anti-Catenin, alpha-1 Antibody (1G5)

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SKU:
A1466-100
£289.03
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Description

Anti-Catenin, alpha-1 Antibody (1G5)is available at Gentaur for Next week Delivery.

Description: Recognizes a protein of 102 kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, α-catenin forms a heterodimer with β-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.

Immunogen Sequence:Human alpha catenin fusion protein

Target Alternative Name:Alpha E-catenin; Cadherin-associated protein; CAP102; Catenin alpha-1; CTNNA1; Renal carcinoma antigen NY-REN-13

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect Catenin, alpha-1 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, WB

Positive Control:WB: A431 and MCF-7 Cell Lysates

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 1-2 ug/ml, WB: 0.5-1ug/ml

Handling:The antibody solution should be gently mixed before use

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Additional Information

Size:
100 µg
Antibody Target:
CTNNA1
Category:
Signal Transduction
Lot Number:
N/A
Host:
Mouse
Antibody Type:
Monoclonal
Isotype:
Mouse IgG1
Accession Number:
P35221
Gene Id:
1495
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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