Anti-Catenin, alpha-1 Antibody (1G5)

Anti-Catenin, alpha-1 Antibody (1G5)is available at Gentaur for Next week Delivery.

Description: Recognizes a protein of 102 kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, α-catenin forms a heterodimer with β-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.

Immunogen Sequence:Human alpha catenin fusion protein

Target Alternative Name:Alpha E-catenin; Cadherin-associated protein; CAP102; Catenin alpha-1; CTNNA1; Renal carcinoma antigen NY-REN-13

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect Catenin, alpha-1 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, WB

Positive Control:WB: A431 and MCF-7 Cell Lysates

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 1-2 ug/ml, WB: 0.5-1ug/ml

Handling:The antibody solution should be gently mixed before use