Anti-Calnexin Antibody (CANX/1541)

Anti-Calnexin Antibody (CANX/1541)is available at Gentaur for Next week Delivery.

Description: It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Immunogen Sequence:Recombinant N-terminal fragment of human Calnexin protein

Target Alternative Name:Calnexin; CANX; CNX; IP90; Major histocompatibility complex class I antigen-binding protein p88; P90

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect Calnexin in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC, WB

Positive Control:IHC: human Renal Cell Carcinoma, human Small Intestinal Carcinoma

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml, WB: 0.5-1ug/ml, IHC: 0.5-1 ug/ml

Handling:The antibody solution should be gently mixed before use