Anti-Caldesmon Antibody (SPM168)

Anti-Caldesmon Antibody (SPM168)is available at Gentaur for Next week Delivery.

Description: Recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

Immunogen Sequence:Crude human uterus extract

Target Alternative Name:CAD, CALD1, Caldesmon 1 Isoform 1, Caldesmon 1 Isoform 2, Caldesmon 1 Isoform 3, Caldesmon 1 Isoform 4, Caldesmon 1 Isoform 5, CDM, HCAD, LCAD, NAG22

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Caldesmon in human samples.

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Uterus

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 1-2 ug/ml, IHC: 0.25-0.5 ug/ml

Handling:The antibody solution should be gently mixed before use.