Anti-c-Myc Oncoprotein Antibody (MYC275)

Anti-c-Myc Oncoprotein Antibody (MYC275)is available at Gentaur for Next week Delivery.

Description: The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

Immunogen Sequence:Recombinant human c-myc protein

Target Alternative Name:Class E basic helix-loop-helix protein 39 (bHLHe39), MRTL, Myc2, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, Transcriptional regulator Myc-A, V-Myc avian myelocytomatosis viral oncogene homolog

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect c-Myc Oncoprotein in human samples.

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Cervical Carcinoma

Application And Usages:FC: 0.5-1ug/1X106 cells in 0.1ml, IF: 1-2ug/ml, IHC: 1-2ug/ml

Handling:The antibody solution should be gently mixed before use.