Anti-Aurora B Rabbit Monoclonal Antibody

Anti-Aurora B Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.

Immunogen Sequence:A peptide corresponding to the C-terminus of human Aurora kinase B

Target Alternative Name:AIK2, AIM-1, ARK-2, AurB, AURKB, Aurora-1, Aurora and Ipl1 like midbody associated protein 1, Aurora kinase B, Aurora-B, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, IPL1, Protein phosphatase 1 regulatory subunit 48 (PPP1R48), Serine/threonine-protein kinase 12, Serine/threonine-protein kinase aurora-B, STK1, STK12, STK5

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Aurora B in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: HeLa cells nontreated (-) or treated (+) with Nocodazole (NOC), WB: human tonsil tissue

Application And Usages:WB: 1:1000-1:2000, IHC: 1:200-1:500

Handling:The antibody solution should be gently mixed before use.