Anti-ATM Antibody

Anti-ATM Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the center region of human ATM

Target Alternative Name:AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1

Species Reactivities:Mouse,Human

Tag Line:Rabbit polyclonal antibody to detect ATM expression in human and mouse samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Immunohistochemistry (IHC),Western Blotting

Positive Control:/

Application And Usages:WB (1:500 - 1:1000), IHC (1:100 - 1:200)

Handling:The antibody solution should be gently mixed before use.