Anti-ATGL Antibody (Clone# ARC1192)

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SKU:
A2238-100
€345
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Description

Anti-ATGL Antibody (Clone# ARC1192)is available at Gentaur for Next week Delivery.

Description: Adipose Triglyceride Lipase (ATGL) is a 54 kDa lipase that belongs to patatin-like phospholipase domain containing (PNPLA) family. It is highly expressed in white and brown adipose tissue whereas a lower expression is detected in other tissues such as the liver, skeletal muscle, lung, and heart. One of the main functions of ATGL is to catalyze the initial step of lipolysis which involves the conversion of triacylglycerol (TAG) to diacylglycerol (DAG). In immune cells (such as macrophages, neutrophils), ATGL promotes pro-inflammatory response by contributing to the production of IL-6 and arachidonic acid, which are precursors of eicosanoids. In non-immune cells (such as heart, adipose tissue, liver, skeletal muscle), it inhibits the production of proinflammatory cytokines and chemokines. ATGL is downregulated in multiple human cancers such as the pancreas, liver, and lung. Mutations in the ATGL gene are associated with neutral lipid storage disease with myopathy.

Immunogen Sequence:Synthetic peptide derived from human ATGL

Target Alternative Name:ATGL, TTS2, PEDF-R, FP17548, TTS-2.2, iPLA2zeta, 1110001C14Rik, PNPLA2, EC 3.1.1.3, Desnutrin, TTS2.2, IPLA2-Zeta

Species Reactivities:Rat,Mouse,Human

Tag Line:Rabbit monoclonal antibody to detect the expression of ATGL in human, mouse, and rat samples

Formulation:In PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH 7.3

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:2000

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 µl
Antibody Target:
ATGL
Category:
Primary antibody
Host:
Rabbit
Antibody Type:
Monoclonal
Isotype:
IgG
Accession Number:
Q96AD5
Gene Id:
57104
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20ºC
Shipping Condition:
Gel Pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
VRAI
Immunocytochemistry Verified:
FAUX
Immunofluorescence Verified:
FAUX
Immunoprecipitation Verified:
FAUX
FACS Verified:
FAUX
ELISA Verified:
FAUX
ChIP Verified:
FAUX
Dot Blot Verified:
FAUX
Flow Cytometry Verified:
FAUX
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