Alpha 2 HS Glycoprotein Antibody

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SKU:
A1111-30T
  • Alpha 2 HS Glycoprotein Antibody
  • Alpha 2 HS Glycoprotein Antibody
$345.93
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Description

Alpha 2 HS Glycoprotein Antibodyis available at Gentaur for Next week Delivery.

Description: Alpha 2 macroglobulin (A2M) is a major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. It functions as a broad-spectrum protease-binding protein. It is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. It is a large plasma glycoprotein that has long been known as an irreversible inhibitor of a variety of proteinases. More recently, it has been reported that numerous growth factors, cytokines and hormones bind to alpha 2M through diverse mechanisms. A2M is also produced in the brain where it binds multiple extracellular ligands and is internalized by neurons and astrocytes. In the brain of Alzheimer's disease (AD) patients, A2M has been localized to diffuse amyloid plaques. A2M also binds soluble beta-amyloid, of which it mediates degradation. Protease-conjugated alpha2-macroglobulin is selectively bound by cells contacting the body fluids and alpha2-macroglobulin and its protease cargo are then internalized and degraded in secondary lysosomes of those cells.

Immunogen Sequence:Human alpha 2 SH Glycoprotein (Cat. No. 7548)

Target Alternative Name:Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect Lactoferrin in human samples.

Formulation:In PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol

Purification: Affinity purified rabbit IgG

Application:WB

Positive Control:WB: h serum, h alpha 2 HS Glycoprotein

Application And Usages:WB: 1-4 µg

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
30 µg
Antibody Target:
AHSG
Category:
Immunology
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P02765
Gene Id:
197
Concentration:
0.5 mg/ml
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Not Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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