Aldolase C (ALDOC) Antibody (CT)

Aldolase C (ALDOC) Antibody (CT)is available at Gentaur for Next week Delivery.

Description: Fructose 1, 6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1, 6-bisphosphate. Fructose 1, 6-bisphosphate aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific aldolase B, and the brain-specific aldolase C. Aldolase A, B, and C arose from a common ancestral gene, from which aldolase B first diverged. Aldolase A is one of the most highly conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

Immunogen Sequence:This ALDOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-333 amino acids from the C-terminal region of human ALDOC.

Target Alternative Name:ALDOC; ALDC; Fructose-bisphosphate aldolase C; Fructose-bisphosphate aldolase C; Brain-type aldolase

Species Reactivities:Human. Predicted cross reactivity with mouse, rat and monkey samples.

Tag Line:Polyclonal Antibody to detect ALDOC in human, mouse, rat and monkey samples.

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application:Western blot, IHC.

Positive Control:Western blot: human brain tissue lysate, IHC: human brain cerebellum.

Application And Usages:Western blot: ~1:1000, IHC: ~1:10-1:50.

Handling:The antibody solution should be gently mixed before use.