Aldolase C (ALDOC) Antibody (CT) Clone # 859CT9.5.3

Aldolase C (ALDOC) Antibody (CT) Clone # 859CT9.5.3is available at Gentaur for Next week Delivery.

Description: Fructose 1, 6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1, 6-bisphosphate. Fructose 1, 6-bisphosphate aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific aldolase B, and the brain-specific aldolase C. Aldolase A, B, and C arose from a common ancestral gene, from which aldolase B first diverged. Aldolase A is one of the most highly conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

Immunogen Sequence:Purified His-tagged ALDOC protein was used to produce this monoclonal antibody.

Target Alternative Name:ALDOC; ALDC; Fructose-bisphosphate aldolase C; Fructose-bisphosphate aldolase C; Brain-type aldolase

Species Reactivities:Human and mouse.

Tag Line:Monoclonal Antibody to detect ALDOC in human and mouse samples.

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Application:Western blot.

Positive Control:Western blot: HL-60,293 cell line and mouse brain, spleen lysates.

Application And Usages:Western blot: ~1:1000.

Handling:The antibody solution should be gently mixed before use.