ALDH5A1 Antibody (NT)

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SKU:
6752-100
€245
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Description

ALDH5A1 Antibody (NT)is available at Gentaur for Next week Delivery.

Description: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH5A1 (aldehyde dehydrogenase 5 family, member A1), also known as SSDH or SSADH, is a 535 amino acid protein that localizes to the mitochondria and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH5A1 is required for gamma-aminobutyric acid (GABA) recycling from the synaptic cleft. Mutations of ALDH5A1 lead to succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) that is characterized by severe ataxia and by mildly retarded psychomotor development.

Immunogen Sequence:This ALDH5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the N-terminal region of human ALDH5A1.

Target Alternative Name:ALDH5A1; SSADH; Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 members A1; NAD (+)-dependent succinic semialdehyde dehydrogenase.

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect ALDH5A1 in human samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Application:Western blot, IHC, FACS.

Positive Control:Western blot: 293 cell lysate, IHC: Human hepatocarcinoma, FACS: ATDC5 cells.

Application And Usages:Western blot: ~1:1000, IHC: ~1:10-1:50, FACS: ~1:10–1:50.

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
100 μl
Antibody Target:
ALDH5A1
Category:
ALDH5A1
Lot Number:
9E026752
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P51649
Gene Id:
7915
Concentration:
N/A
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Verified
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