VEGFR2, human recombinant

VEGFR2, human recombinant is available at Gentaur for Next week delivery.

Receptor for VEGF

Biomolecule/Target:

Alternates names: Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

Synonyms: Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

Background Information: VEGFR-2 has a lower affinity for VEGF than the Flt-1 receptor, but a higher signaling activity. Mitogenic activity in endothelial cells is mainly mediated by VEGFR-2 leading to their proliferation. No naturally occurring, secreted forms of VEGFR-2 have so far been reported. The binding of VEGF165 to VEGFR-2 is dependent on heparin. Soluble VEGFR-2 Human Recombinant produced in baculovirus is monomeric, glycosylated, polypeptide having a molecular mass of 116 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding. The sKDR is purified by proprietary chromatographic techniques.

Reconstitution Instructions: Reconstitute in sterile water to a concentration not less than 0.1 mg/ml. This solution can then be stored at 4°C for 2-7 days. For future use for future use; For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA) then store at –20°C. Avoid freeze-thaw cycles.

NCBI Gene Symbol: VEGFR2

Gene ID: 3791

NCBI Accession: P35968