VAP-1, human recombinant

VAP-1, human recombinant is available at Gentaur for Next week delivery.

Plays an important role in the migration of lymphocytes to inflamed tissue

Biomolecule/Target: VAP1

Alternates names: Vascular Adhesion Protein-1, AOC3, SSAO, HPAO, Copper Amine Oxidase, Membrane Primary Amine Oxidase

Synonyms: Vascular Adhesion Protein-1, AOC3, SSAO, HPAO, Copper Amine Oxidase, Membrane Primary Amine Oxidase

Background Information: VAP-1 is a type II membrane cell adhesion protein belonging to the copper/topaquinone oxidase family. It is primarily expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. VAP-1 can catalyze the oxidative deamination of low molecular weight amines, and plays an important role in the migration of lymphocytes to inflamed tissue. Inhibition of VAP-1 can protect against inflammation related damage to certain injured tissues. Additionally, VAP-1 can function as a significant prognostic marker for certain cancers and cardiovascular diseases. Recombinant VAP-1 is a mixture of monomeric and disulfide linked homodimeric forms of a 737 amino acid polypeptide corresponding to amino acids 27 to 763 of the VAP-1 precursor.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: VAP1

Gene ID: 8639

NCBI Accession: Q16853