Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE)

Recombinant Bovine Coronavirus Hemagglutinin-esterase (HE) is available at Gentaur for Next week delivery.

Structural protein that makes short spikes at the surface of the virus.

Biomolecule/Target:

Alternates names: Hemagglutinin-esterase, HE protein, E3 glycoprotein, HE

Synonyms: Hemagglutinin-esterase, HE protein, E3 glycoprotein, HE

Background Information: Structural protein that makes short spikes at the surface of the virus. It contains receptor binding and receptor-destroying activities and mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps to prevent self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. It seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.

Reconstitution Instructions: Centrifuge the vial briefly. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

NCBI Gene Symbol: HE

Gene ID:

NCBI Accession: P15776