RASSF1A, human recombinant

RASSF1A, human recombinant is available at Gentaur for Next week delivery.

Potential tumor suppressor

Biomolecule/Target: RASSF1

Alternates names: Ras association domain-containing protein 1, 123F2, NORE2A, RASSF1, RDA32, REH3P21

Synonyms: Ras association domain-containing protein 1, 123F2, NORE2A, RASSF1, RDA32, REH3P21

Background Information: RASSF1A is similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. This protein required for death receptor-dependent apoptosis. Recombinant human RASSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli.

Reconstitution Instructions: N/A

NCBI Gene Symbol: RASSF1

Gene ID: 11186

NCBI Accession: Q9NS23