Pyrroline-5-caroxylate reductase, M. tuberculosis Recombinant

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SKU:
P1456-50
€185
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Description

Pyrroline-5-caroxylate reductase, M. tuberculosis Recombinant is available at Gentaur for Next week delivery.

Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline

Biomolecule/Target:

Alternates names: P5CR, PCA reductase, P5C reductase, proC

Synonyms: P5CR, PCA reductase, P5C reductase, proC

Background Information: P5CR catalyzes the NADH dependent reaction of converting pyrroline-5-caboxylate to proline. It is important for regulating amino acid metabolism, intracellular redox potential, and apoptosis. Increased P5CR expression and activity have been observed in carcinoma and pulmonary tumors.

Reconstitution Instructions: Reconstitute the lyophilized protein with 30% Glycerol and 5 mM BME at the concentration of 0.5 mg/ml. Incubate the reconstituted protein at 25 °C for 15 minutes.

NCBI Gene Symbol: proC

Gene ID: 887256

NCBI Accession: P9WHU7

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Additional Information

Size:
50 µg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
N/A
Gene Source:
Mycobacterium tuberculosis
Recombinant:
False
Source:
E. coli
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Biological activity:
This enzyme has a specific activity of ≥ 7 mU/mg based on its conversion of proline to pyrroline-5-caboxylate.
Molecular Weight:
49.4 kDa with N-terminal TRX tag
Storage Temperature:
-20ºC
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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