Protein Disulfide Isomerase (PDI), human recombinant

Protein Disulfide Isomerase (PDI), human recombinant is available at Gentaur for Next week delivery.

Catalyzes disulfide exchange and protein folding

Biomolecule/Target:

Alternates names: Protein Disulfide Isomerase, Cellular thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55

Synonyms: Protein Disulfide Isomerase

Background Information: Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide bonds formation, reduction, or isomerization of newly synthesized proteins in the lumen of the endoplasmic reticulum (ER). Human Protein Disulfide Isomerase is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI has been found to have moderate effects (25-fold) on the rate of oxidative folding of proteins in vitro. Recombinant Human PDI produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 508 amino acids and having a molecular mass of 57.1 kDa. The human PDI contains N-terminal 6xHis-tag and is purified by proprietary chromatographic techniques.

Reconstitution Instructions: Reconstituted PDI should be stored in working aliquots at -20°C. For long-term storage, it is recommended to add carrier protein (0.1% HAS or BSA).

NCBI Gene Symbol: PDIA3

Gene ID: 2923

NCBI Accession: P30101