Prekallikrein, Human Plasma

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SKU:
7685-100
€185
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Description

Prekallikrein, Human Plasma is available at Gentaur for Next week delivery.

Activates plasminogen in fibrinolysis and cleaves kininogen in the bradykinin system of vasodilation.

Biomolecule/Target: Prekallikrein

Alternates names: Fletcher factor, Kininogenin.

Synonyms: Fletcher factor, Kininogenin.

Background Information: Prekallikrein is the glycosylated single chain zymogen precursor of the plasma serine protease kallikrein. Plasma prekallikrein circulates with kininogen and is activated by Factor XIIa in the intrinsic coagulation pathway. Kallikrein activates plasminogen in fibrinolysis and cleaves kininogen in the bradykinin system of vasodilation. Prekallikrein deficiency is rare and causes increased activated partial thromboplastin time. Elevated plasma prekallikrein is associated with diabetes and cardiovascular disease.

Reconstitution Instructions: N/A

NCBI Gene Symbol: KLK

Gene ID: 3818

NCBI Accession: P03952

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Additional Information

Size:
100 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
No
Source:
Human Plasma
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Lot dependent
Results:
Lot dependent
Molecular Weight:
86 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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