Description
NME2, human recombinant is available at Gentaur for Next week delivery.
A heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase.
Biomolecule/Target: NME2
Alternates names: Nucleoside diphosphate kinase B, NDPK-B, NDPKB, NM23-H2, NM23B.
Synonyms: Nucleoside diphosphate kinase B, NDPK-B, NDPKB, NM23-H2, NM23B.
Background Information: NME2, also known as NM23B, is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways. Recombinant human NME2 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Reconstitution Instructions: N/A
NCBI Gene Symbol: NME2
Gene ID: 4831
NCBI Accession: P22392
Additional Information
Size: |
100 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli. |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Specific activity is > 340 units/ml, in which one unit will convert 1.0 µmole each of TDP and ATP to TTP and ADP per minute at pH 7.6 at 25ºC in a coupled system with PK/LDH. |
Results: |
Specific activity is > 340 units/ml |
Molecular Weight: |
17.2 kDa (152 aa, 1-152 aa) |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
1 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |
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