Description
Myostatin, human recombinant is available at Gentaur for Next week delivery.
A secreted growth differentiation factor
Biomolecule/Target: Myostatin
Alternates names: GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy
Synonyms: GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy
Background Information: Myostatin, also known as Growth Differentiation Factor-8 (GDF-8), belongs to the TGF-β superfamily. Along with other members of the TGF-β family, Myostatin plays a crucial role as a regulator for embryonic development and tissue homeostasis in adult animals. Early studies show that Myostatin has the ability to halt muscle growth. New research has further suggested that Myostatin may also be involved in reducing and preventing adiposity and type-2 diabetes. Human Myostatin is a homodimeric protein with each subunit containing 109 amino acid residues with a total molecular weight of 24.8 kDa.
Reconstitution Instructions: It is recommended to reconstitute the lyophilized human Myostatin in sterile 20 mM acetic acid to a concentration of 0.1 to 1.0 mg/ml. This solution can then be diluted into other aqueous buffers.
NCBI Gene Symbol: GDF8
Gene ID: 2660
NCBI Accession: O14793
Additional Information
Size: |
50 μg |
Adwords: |
Yes |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Determined by its ability to inhibit the proliferation of MPC-11 cells. The ED₅₀ for this effect is <20 ng/ml. |
Results: |
<20 ng/ml |
Molecular Weight: |
24.8 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |
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