MIP-3/CCL23, human recombinant

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SKU:
7175-50
€185
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Description

MIP-3/CCL23, human recombinant is available at Gentaur for Next week delivery.

Chemoattracts monocytes, resting T-lymphocytes and neutrophils

Biomolecule/Target: CCL23

Alternates names: Macrophage Inflammatory Protein-3, CCL23, MPIF-1, Ck-β8

Synonyms: Macrophage Inflammatory Protein-3, CCL23, MPIF-1, Ck-β8

Background Information: MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol: CCL23

Gene ID: 6368

NCBI Accession: P55773

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. Coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
< 0.1 ng/μg of protein (<1EU/μg).
Activity (Specifications/test method):
Determined by its ability to chemoattract human T cells using a concentration
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