MART-1/Melan-A, mouse recombinant

MART-1/Melan-A, mouse recombinant is available at Gentaur for Next week delivery.

Pure mouse recombinant full length MART-1/Melan-A.

Biomolecule/Target: MART-1/Melan-A

Alternates names: Melanoma antigen recognized by T-cells 1, Antigen LB39-AA, Antigen SK29-AA, MART-1, Melan-A

Synonyms: Melanoma antigen recognized by T-cells 1, Antigen LB39-AA, Antigen SK29-AA, MART-1, Melan-A

Background Information: MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Mouse MART-1 is purified by proprietary chromatographic techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: Melan-A

Gene ID: 77836

NCBI Accession: Q2TA50