LSD1, Human Recombinant

LSD1, Human Recombinant is available at Gentaur for Next week delivery.

Active human recombinant Lysine (K)-specific demethylase 1 protein

Biomolecule/Target:

Alternates names: Human Recombinant LSD,LSD, Human Recombinant,Human Recombinant LSD1,Lysine-specific histone demethylase, 1KDM1, BHC110, AOF2, KIAA0601, KDM1A, lysine (K)-specific demethylase 1A

Synonyms: Human Recombinant LSD,LSD, Human Recombinant,Human Recombinant LSD1,Lysine-specific histone demethylase, 1KDM1, BHC110, AOF2, KIAA0601, KDM1A, lysine (K)-specific demethylase 1A

Background Information: The mono, di- and trimethylation of particular lysine residues in histone tails (e.g. histone H3 lysine-4 (H3K4), H3K9, H3K27, H3K36, H4K20) are implicated in the transmission of heritable epigenetic information and the control of chromatin structure and DNA transcription. LSD1 catalyzes the oxidative demethylation of mono- and dimethylated H3K4, producing hydrogen peroxide and formaldehyde in the process. H3K4 methylation is considered a transcription activating chromatin mark. In vivo LSD1 is frequently found in association with the transcriptional corepressor protein CoREST and HDACs 1 or 2. Its expression is elevated in a number of cancers, which makes it a promising target for drug development. LSD1 is inhibited by a number of established monoamine oxidase inhibitor drugs.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID:

NCBI Accession: BAA25527