Leptin, human recombinant

(No reviews yet) Write a Review
SKU:
4366-5
€185
Frequently bought together:

Description

Leptin, human recombinant is available at Gentaur for Next week delivery.

Adipose-derived hormone which regulates energy intake & energy expenditure

Biomolecule/Target: Leptin

Alternates names: OB Protein, Obesity Protein, OBS, Obesity factor.

Synonyms: OB Protein, Obesity Protein, OBS, Obesity factor.

Background Information: Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body’s fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Human Leptin is a 16 kDa protein containing 146 amino acid residues.

Reconstitution Instructions: Add 15 mM sterile HCl (0.5 ml/1 mg vial or 5 ml/10 mg vial) to the vial. After the protein is completely dissolved, add 7.5 mM sterile NaOH (0.3 ml/1 mg vial or 3 ml/10 mg vial) to bring the pH to approximately 5.2.

NCBI Gene Symbol: LEP

Gene ID: 3952

NCBI Accession: P41159

View AllClose

Additional Information

Size:
5 mg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
BioVision’s human Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 mg Leptin/gm of body weight for 7 days.
Results:
N/A
Molecular Weight:
16.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose