IMPAD1, human recombinant

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SKU:
7812-10
€185
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Description

IMPAD1, human recombinant is available at Gentaur for Next week delivery.

Catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP).

Biomolecule/Target: IMPAD1

Alternates names: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3

Synonyms: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3

Background Information: IMPAD1, also known as Inositol monophosphatase 3, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Recombinant human IMPAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Reconstitution Instructions: N/A

NCBI Gene Symbol: IMPAD1

Gene ID: 54928

NCBI Accession: Q9NX62

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Additional Information

Size:
10 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli.
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
Specific activity > 3300 pmole/min/µg, its ability to dephosphorylate adenosine 3’5’-diphosphate sodium salt at pH 7.5, 25ºC.
Results:
Specific activity > 3300 pmole/min/µg
Molecular Weight:
37.6 kDa (349 aa, 34-359 aa + His Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
0.25 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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