Description
IMPAD1, human recombinant is available at Gentaur for Next week delivery.
Catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP).
Biomolecule/Target: IMPAD1
Alternates names: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3
Synonyms: Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3
Background Information: IMPAD1, also known as Inositol monophosphatase 3, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Recombinant human IMPAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Reconstitution Instructions: N/A
NCBI Gene Symbol: IMPAD1
Gene ID: 54928
NCBI Accession: Q9NX62
Additional Information
Size: |
10 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli. |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Specific activity > 3300 pmole/min/µg, its ability to dephosphorylate adenosine 3’5’-diphosphate sodium salt at pH 7.5, 25ºC. |
Results: |
Specific activity > 3300 pmole/min/µg |
Molecular Weight: |
37.6 kDa (349 aa, 34-359 aa + His Tag) |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
0.25 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |