IL-17F, murine recombinant

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SKU:
4177F-25
€185
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Description

IL-17F, murine recombinant is available at Gentaur for Next week delivery.

A proinflammatory cytokine produced by activated T cells

Biomolecule/Target: IL-17F

Alternates names: IL-17, Interleukin 17, Cytokine ML-1, Interleukin-24

Synonyms: none

Background Information: Homodimeric interleukin-17F is a member of the IL-17 family of six homodimeric proteins (IL-17A-17F). Activated CD4+ T cells have also been shown to produce Mouse IL-17F. Activity studies reveal IL-17A to be the most potent, followed by IL-17A/F and IL-17F 100 fold lower than IL-17A. Recombinant Mouse IL-17F produced in E.Coli is a non-glycosylated polypeptide comprised of two monomeric subunit each of mIL-17F. The dimer consists of 266 amino acids, with an approximate molecular weight of 29.8 kDa.

Reconstitution Instructions: Reconstitute in sterile H₂O to a concentration of 0.1 mg/ml (Note: Gently pipetting to dissolve). The solution can then be diluted into other aqueous buffers.

NCBI Gene Symbol: IL-17F

Gene ID: 257630

NCBI Accession: Q7TNI7

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Additional Information

Size:
25 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
IL-17F is fully bioactive when compared to standard. The ED₅₀ as determined by the dose-dependent induction of IL-6 in NHDF is 1.94 ng/ml.
Results:
1.94 ng/ml
Molecular Weight:
29.8 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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