Description
IL-17F, human recombinant is available at Gentaur for Next week delivery.
A proinflammatory cytokine produced by activated T cells
Biomolecule/Target: IL-17F
Alternates names: IL-17, Interleukin 17, Cytokine ML-1, Interleukin-24
Synonyms: none
Background Information: IL-17Fis a member of the IL-17 family of structurally-related cytokines. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F stimulates proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant human IL-17F is a 30.1 kDa consisting of two 134 amino acid polypeptide chains.
Reconstitution Instructions: The lyophilized IL-17F can be reconstituted in H₂O to a concentration of 0.1-1.0 µg/µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
NCBI Gene Symbol: IL17F
Gene ID: 112744
NCBI Accession: Q96PD4
Additional Information
Size: |
25 μg |
Adwords: |
Yes |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED₅₀ as determined by the dose-dependent induction of IL-6 in NIH-3T3 cells was found to be approximately 10 ng/ml, corresponding to a specific activity of 1.0 x 10⁵ IU/mg |
Results: |
10 ng/ ml |
Molecular Weight: |
30.1 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |
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